Protein Name phosphoenolpyruvate carboxykinase 1
Organism Rattus norvegicus
Gene ID 362282
Gene Symbol


UniProt P07379 (PCKGC_RAT)
Relationships Total Number of functionally related compound(s) : 395
Total Number of Articles : 455

phosphoenolpyruvate carboxykinase 1

Gene Summary

Enables several functions, including guanyl ribonucleotide binding activity; manganese ion binding activity; and nucleoside diphosphate kinase activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to hexose stimulus; and cellular response to organonitrogen compound. Located in cytoplasm. Used to study type 2 diabetes mellitus. Biomarker of non-alcoholic steatohepatitis. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human PCK1 (phosphoenolpyruvate carboxykinase 1). [provided by Alliance of Genome Resources, Apr 2022]

  • phosphoenolpyruvate carboxykinase, cytosolic [GTP]
  • phosphoenolpyruvate carboxykinase (GTP)
  • phosphoenolpyruvate carboxykinase 1 (soluble)
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