Title : The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy.

Pub. Date : 1998 Sep 15

PMID : 9753690






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 As an enzyme of the thymidylate synthase metabolic cycle, SHMT catalyses the retro-aldol cleavage of serine to glycine, with the resulting hydroxymethyl group being transferred to tetrahydrofolate to form 5, 10-methylene-tetrahydrofolate. Glycine serine hydroxymethyltransferase 1 Homo sapiens