Title : Decreases in brain glial fibrillary acidic protein (GFAP) are associated with increased serum corticosterone following inhalation exposure to toluene.

Pub. Date : 1998 Aug-Oct

PMID : 9745935






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Decreases in brain glial fibrillary acidic protein (GFAP) are associated with increased serum corticosterone following inhalation exposure to toluene. Toluene glial fibrillary acidic protein Rattus norvegicus
2 Decreases in brain glial fibrillary acidic protein (GFAP) are associated with increased serum corticosterone following inhalation exposure to toluene. Toluene glial fibrillary acidic protein Rattus norvegicus
3 Toluene and other neurotoxicants can cause both increases and decreases in the concentration of GFAP in the brain. Toluene glial fibrillary acidic protein Rattus norvegicus
4 In order to identify conditions under which inhalation exposure to toluene results in decreased GFAP concentration, rats were subjected to repeated inhalation of toluene for up to 7 days. Toluene glial fibrillary acidic protein Rattus norvegicus
5 This toluene exposure replicated the previously-observed decreases in GFAP in the thalamus. Toluene glial fibrillary acidic protein Rattus norvegicus
6 More research is needed to firmly establish cause and effect between increased serum glucocorticoid levels and GFAP decreases following toluene inhalation and to determine whether these decreases indicate toxicity or adaptive changes. Toluene glial fibrillary acidic protein Rattus norvegicus