Protein Name glial fibrillary acidic protein
Organism Rattus norvegicus
Gene ID 24387
Gene Symbol

Gfap

UniProt P47819 (GFAP_RAT)
Relationships Total Number of functionally related compound(s) : 722
Total Number of Articles : 1105
Description

glial fibrillary acidic protein

Gene Summary

Enables integrin binding activity and kinase binding activity. A structural constituent of cytoskeleton. Involved in positive regulation of glial cell proliferation and regulation of chaperone-mediated autophagy. Located in astrocyte projection and cytoplasmic side of lysosomal membrane. Biomarker of brain edema and retinal disease. Human ortholog(s) of this gene implicated in Alexander disease. Orthologous to human GFAP (glial fibrillary acidic protein). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • glial fibrillary acidic protein
  • glial fibrillary acidic protein alpha
  • glial fibrillary acidic protein delta
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Properties