Title : Functional activation of lymphocyte CD44 in peripheral blood is a marker of autoimmune disease activity.

Pub. Date : 1998 Sep 15

PMID : 9739051






1 Functional Relationships(s)
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Protein Name
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1 CD44 on lymphocytes that has been "activated" to bind its principal ligand hyaluronate (HA) on endothelium can mediate the primary adhesion (rolling) of lymphocytes to vascular endothelial cells under conditions of physiologic shear stress, and this interaction is used for activated T cell extravasation into an inflamed site in vivo in mice (DeGrendele, H.C., P. Estess, L.J. ha CD44 antigen Mus musculus