Title : The L-arginine inhibition of rat middle cerebral artery contractile responses is mediated by inducible nitric oxide synthase.

Pub. Date : 1998 Apr

PMID : 9730265






3 Functional Relationships(s)
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1 Pre-incubation of segments with dexamethasone (1 microM), to inhibit inducible NOS (iNOS), or with the antibiotic polymyxin B (10 microg ml(-1)) reduced the L-Arg inhibition, whereas it was increased by lipopolysaccharide (LPS, 100 ng ml(-1)), an inductor of iNOS. Dexamethasone nitric oxide synthase 2 Rattus norvegicus
2 Pre-incubation of segments with dexamethasone (1 microM), to inhibit inducible NOS (iNOS), or with the antibiotic polymyxin B (10 microg ml(-1)) reduced the L-Arg inhibition, whereas it was increased by lipopolysaccharide (LPS, 100 ng ml(-1)), an inductor of iNOS. Dexamethasone nitric oxide synthase 2 Rattus norvegicus
3 Pre-incubation of segments with dexamethasone (1 microM), to inhibit inducible NOS (iNOS), or with the antibiotic polymyxin B (10 microg ml(-1)) reduced the L-Arg inhibition, whereas it was increased by lipopolysaccharide (LPS, 100 ng ml(-1)), an inductor of iNOS. Dexamethasone nitric oxide synthase 2 Rattus norvegicus