Title : Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.

Pub. Date : 1998 Sep 1

PMID : 9724521






1 Functional Relationships(s)
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1 The structures of both thrombin and trypsin complexes show similar well-defined transition states in the S1 site and at the electrophilic carbon atom and Ser195OG. Carbon coagulation factor II, thrombin Homo sapiens