Pub. Date : 1998 Jun
PMID : 9720761
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | With the recent cloning of PLD isoenzymes, their association with low-molecular-weight G proteins, protein kinase C and tyrosine kinases, the availability of antibodies and an understanding of the role of PLD product, phosphatidic acid (PA), in cell physiology, the field is gaining momentum. | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 2 | With the recent cloning of PLD isoenzymes, their association with low-molecular-weight G proteins, protein kinase C and tyrosine kinases, the availability of antibodies and an understanding of the role of PLD product, phosphatidic acid (PA), in cell physiology, the field is gaining momentum. | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 3 | In this review, we will explore the molecular properties of mammalian PLD and its gene(s), the complexity of this enzyme regulation and the myriad physiological roles for PLD and PA and related metabolic products, with particular emphasis on a role in the activation of NADPH oxidase, or respiratory burst, leading to the generation of oxygen radicals. | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |