Title : Alpha-difluoromethylornithine (DFMO) as a potent arginase activity inhibitor in human colon carcinoma cells.

Pub. Date : 1998 Apr 15

PMID : 9719479






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 L-ornithine, a substrate for ODC, retroinhibits arginase. Ornithine ornithine decarboxylase 1 Homo sapiens
2 The inhibitory effect of DFMO upon arginase, one step upstream of the ODC reaction in the metabolic conversion of L-arginine to polyamines, is of potential physiological importance, since it could alter the production of ornithine and thus its metabolism in pathways other than the ODC pathway. Ornithine ornithine decarboxylase 1 Homo sapiens
3 The inhibitory effect of DFMO upon arginase, one step upstream of the ODC reaction in the metabolic conversion of L-arginine to polyamines, is of potential physiological importance, since it could alter the production of ornithine and thus its metabolism in pathways other than the ODC pathway. Ornithine ornithine decarboxylase 1 Homo sapiens