Title : Molecular mechanisms of loss of beta 2-microglobulin expression in drug-resistant breast cancer sublines and its involvement in drug resistance.

Pub. Date : 1998 Aug 18

PMID : 9709006






2 Functional Relationships(s)
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1 Moreover, beta 2m mRNA remained undetectable in MCF-7/Adr cells following cycloheximide treatment. Cycloheximide beta-2-microglobulin Homo sapiens
2 However, in MCF-7 cells, increased beta 2m mRNA was observed after 12 h, and a similar level of increased mRNA expression was observed after 36 h of cycloheximide treatment in MCF-7/Adr-5 cells; these results suggest that one of the mechanisms controlling beta 2m mRNA expression might be a negative regulatory protein in MCF-7/Adr-5 cells. Cycloheximide beta-2-microglobulin Homo sapiens