Title : Calorie restriction reduces ulcerative dermatitis and infection-related mortality in p53-deficient and wild-type mice.

Pub. Date : 1998 Aug

PMID : 9699732






6 Functional Relationships(s)
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1 CR also extended life span in p53(+/-) mice, but 50% of p53(+/-) mice subjected to CR still developed skin ulcers and mean life span was shorter than that seen in WT mice. Chromium transformation related protein 53, pseudogene Mus musculus
2 CR also extended life span in p53(+/-) mice, but 50% of p53(+/-) mice subjected to CR still developed skin ulcers and mean life span was shorter than that seen in WT mice. Chromium transformation related protein 53, pseudogene Mus musculus
3 Differences in response to CR between WT and p53(+/-) mice may be due to the reduction in p53 gene dosage, dissimilarity in the application of the CR treatment, or both. Chromium transformation related protein 53, pseudogene Mus musculus
4 Differences in response to CR between WT and p53(+/-) mice may be due to the reduction in p53 gene dosage, dissimilarity in the application of the CR treatment, or both. Chromium transformation related protein 53, pseudogene Mus musculus
5 Differences in response to CR between WT and p53(+/-) mice may be due to the reduction in p53 gene dosage, dissimilarity in the application of the CR treatment, or both. Chromium transformation related protein 53, pseudogene Mus musculus
6 These results suggest that some of the beneficial effects of CR may need full expression of p53 for complete realization. Chromium transformation related protein 53, pseudogene Mus musculus