Title : Depressed renal and vascular nitric oxide synthase expression in cyclosporine-induced hypertension.

Pub. Date : 1998 Aug

PMID : 9690215






3 Functional Relationships(s)
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1 The fall in renal iNOS protein in CsA-treated rats was accompanied by a parallel decline in iNOS mRNA abundance and enzymatic activity. Cyclosporine nitric oxide synthase 2 Rattus norvegicus
2 The fall in renal iNOS protein in CsA-treated rats was accompanied by a parallel decline in iNOS mRNA abundance and enzymatic activity. Cyclosporine nitric oxide synthase 2 Rattus norvegicus
3 CONCLUSION: Administration of CsA for three weeks resulted in a significant rise in BP together with marked reductions in urinary NOx excretion, and renal and vascular iNOS expression. Cyclosporine nitric oxide synthase 2 Rattus norvegicus