Title : Ligand-dependent regulation of NPR-A gene expression in inner medullary collecting duct cells.

Pub. Date : 1998 Jul

PMID : 9689013






3 Functional Relationships(s)
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1 8-Bromo-cGMP was also effective in inhibiting NPR-A mRNA levels and NPR-A promoter activity, suggesting that the second messenger (i.e., cGMP) rather than ANP, itself, is responsible for downregulation of NPR-A gene expression. Cyclic GMP natriuretic peptide receptor 1 Homo sapiens
2 8-Bromo-cGMP was also effective in inhibiting NPR-A mRNA levels and NPR-A promoter activity, suggesting that the second messenger (i.e., cGMP) rather than ANP, itself, is responsible for downregulation of NPR-A gene expression. Cyclic GMP natriuretic peptide receptor 1 Homo sapiens
3 8-Bromo-cGMP was also effective in inhibiting NPR-A mRNA levels and NPR-A promoter activity, suggesting that the second messenger (i.e., cGMP) rather than ANP, itself, is responsible for downregulation of NPR-A gene expression. Cyclic GMP natriuretic peptide receptor 1 Homo sapiens