Title : Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat.

Pub. Date : 1998

PMID : 9681931






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat. Caffeine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 By using in situ hybridisation we examined the acute effects of caffeine on haloperidol-induced c-fos mRNA in rat striatum. Caffeine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 Similar region-specific effects of caffeine were observed on c-fos mRNA induced by the selective dopamine D2 antagonist raclopride (0.5 mg kg(-1)). Caffeine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
4 Both haloperidol and raclopride counteracted caffeine-induced c-fos mRNA expression in somatosensory cortex. Caffeine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
5 The present data show that caffeine modulates c-fos mRNA induced by dopamine D2 receptor antagonism differentially in sensorimotor and limbic-related areas of striatum. Caffeine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus