Title : Induction of the vitamin D 24-hydroxylase (CYP24) by 1,25-dihydroxyvitamin D3 is regulated by parathyroid hormone in UMR106 osteoblastic cells.

Pub. Date : 1998 Aug

PMID : 9681485






2 Functional Relationships(s)
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1 These studies demonstrate that PTH in the presence of 1,25(OH)2D works through the cAMP-dependent signaling pathway to increase transcription of the CYP24 gene, to increase CYP24 protein levels, and to increase 24-hydroxylase activity. Cyclic AMP cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus
2 These studies demonstrate that PTH in the presence of 1,25(OH)2D works through the cAMP-dependent signaling pathway to increase transcription of the CYP24 gene, to increase CYP24 protein levels, and to increase 24-hydroxylase activity. Cyclic AMP cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus