Protein Name cytochrome P450, family 24, subfamily a, polypeptide 1
Organism Rattus norvegicus
Gene ID 25279
Gene Symbol

Cyp24a1

UniProt Q09128 (CP24A_RAT)
Relationships Total Number of functionally related compound(s) : 102
Total Number of Articles : 99
Description

cytochrome P450, family 24, subfamily a, polypeptide 1

Gene Summary

Enables 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; 25-hydroxycholecalciferol-24-hydroxylase activity; and vitamin D 25-hydroxylase activity. Involved in vitamin D catabolic process. Predicted to be located in mitochondrion and nucleoplasm. Human ortholog(s) of this gene implicated in hypercalcemia. Orthologous to human CYP24A1 (cytochrome P450 family 24 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
  • 25-hydroxyvitamin D3 24-hydroxylase
  • 25-hydroxyvitaminD324-hydroxylase
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Properties