Title : Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb.

Pub. Date : 1998 Jul

PMID : 9675054






2 Functional Relationships(s)
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1 In both experimental paradigms we observed significantly more BrdU-labeled cells in the olfactory bulbs on the BDNF-infused side than in the olfactory bulb of PBS-infused animals. Bromodeoxyuridine brain-derived neurotrophic factor Rattus norvegicus
2 Analysis of the BDNF-infused brains of animals injected intraperitoneally with BrdU demonstrated a 100% increase in the number of BrdU-labeled cells in the bulb, the preponderance ( approximately 90%) of which were double-labeled with a neuron-specific antibody. Bromodeoxyuridine brain-derived neurotrophic factor Rattus norvegicus