Title : Pharmacological evaluation of [11C]A-84543: an enantioselective ligand for in vivo studies of neuronal nicotinic acetylcholine receptors.

Pub. Date : 1998

PMID : 9667769






1 Functional Relationships(s)
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1 The nAChR agonists (-)nicotine, cytisine, and (+) epibatidine reduced the radioactivity due to [11C]A-84543 in the superior colliculus by 41%, 38%, and 27%, respectively, while lobeline, which also interacts with central nAChRs, produced a 24% inhibition. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus