Title : Regulation of angiotensin II-induced neuromodulation by MARCKS in brain neurons.

Pub. Date : 1998 Jul 13

PMID : 9660875






3 Functional Relationships(s)
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1 Furthermore, depletion of MARCKS by MARCKS-AON treatment of neurons resulted in a significant decrease in Ang II-stimulated accumulation of TH and DbetaH immunoreactivities and [3H]NE uptake activity in synaptosomes. Tritium myristoylated alanine rich protein kinase C substrate Homo sapiens
2 Furthermore, depletion of MARCKS by MARCKS-AON treatment of neurons resulted in a significant decrease in Ang II-stimulated accumulation of TH and DbetaH immunoreactivities and [3H]NE uptake activity in synaptosomes. Tritium myristoylated alanine rich protein kinase C substrate Homo sapiens
3 MARCKS pep148-165, which contains PKC phosphorylation sites, inhibited Ang II stimulation of MARCKS phosphorylation and reduced the amount of TH, DbetaH, and [3H]NE uptake in neuronal synaptosomes. Tritium myristoylated alanine rich protein kinase C substrate Homo sapiens