Protein Name myristoylated alanine rich protein kinase C substrate
Organism Homo sapiens
Gene ID 4082
Gene Symbol

MARCKS

UniProt P29966 (MARCS_HUMAN), Q6NVI1 (Q6NVI1_HUMAN)
Relationships Total Number of functionally related compound(s) : 254
Total Number of Articles : 272
Description

myristoylated alanine rich protein kinase C substrate

Gene Summary

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]

synonyms
  • myristoylated alanine-rich C-kinase substrate
  • myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)
  • phosphomyristin
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Properties