Title : Treatment of rats during pubertal development with 2,3,7,8-tetrachlorodibenzo-p-dioxin alters both signaling kinase activities and epidermal growth factor receptor binding in the testis and the motility and acrosomal reaction of sperm.

Pub. Date : 1998 Jun

PMID : 9653074






2 Functional Relationships(s)
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1 Treatment of rats during pubertal development with 2,3,7,8-tetrachlorodibenzo-p-dioxin alters both signaling kinase activities and epidermal growth factor receptor binding in the testis and the motility and acrosomal reaction of sperm. Polychlorinated Dibenzodioxins epidermal growth factor receptor Rattus norvegicus
2 These findings provide evidence for involvement of Src kinase signaling and EGFR in the mechanism by which TCDD disrupts testicular development and subsequently affects testis function. Polychlorinated Dibenzodioxins epidermal growth factor receptor Rattus norvegicus