Title : Nitrogen mustard up-regulates Bcl-2 and GSH and increases NTP and PCr in HT-29 colon cancer cells.

Pub. Date : 1998 May

PMID : 9652754






1 Functional Relationships(s)
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1 We hypothesized that unexplained increases in nucleoside triphosphates (NTP) observed by 31P magnetic resonance spectroscopy (MRS) after treatment of tumours by DNA-damaging agents were related to chemotherapy-induced up-regulation of the bcl-2 gene and DNA damage prevention and repair processes. nucleoside triphosphates BCL2 apoptosis regulator Homo sapiens