Pub. Date : 1998 Jun 18
PMID : 9642111
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Molecular cloning and expression of human cGMP-binding cGMP-specific phosphodiesterase (PDE5). | Cyclic GMP | phosphodiesterase 5A | Homo sapiens |
| 2 | A human PDE5 cDNA has been isolated which contains an open reading frame encoding an 875 amino acid, 100,012 Da polypeptide, the expression of which yields a protein of the predicted size and is capable of hydrolyzing cGMP. | Cyclic GMP | phosphodiesterase 5A | Homo sapiens |
| 3 | The deduced amino acid sequence is very similar (95%) to that of bovine PDE5, and comprises a conserved cGMP-binding domain and catalytic domain. | Cyclic GMP | phosphodiesterase 5A | Homo sapiens |