Title : Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line.

Pub. Date : 1998 May

PMID : 9635842






2 Functional Relationships(s)
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1 Importantly, the efflux rates of TPT in the IGROV-1 and IGROV(T100r) cell lines were not significantly different and were shown to be independent on P-glycoprotein (P-gp) or multidrug resistance-associated protein (MRP). Topotecan ATP binding cassette subfamily B member 1 Homo sapiens
2 Importantly, the efflux rates of TPT in the IGROV-1 and IGROV(T100r) cell lines were not significantly different and were shown to be independent on P-glycoprotein (P-gp) or multidrug resistance-associated protein (MRP). Topotecan ATP binding cassette subfamily B member 1 Homo sapiens