Title : Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A.

Pub. Date : 1998 May 15

PMID : 9633991






1 Functional Relationships(s)
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1 Cyp2e1(-/-) and Cyp1a2(-/-) mice are more resistant to acetaminophen hepatotoxicity than wild-type strains, even though the amounts of the other forms of P450s are unaltered in the liver. Acetaminophen cytochrome P450, family 1, subfamily a, polypeptide 2 Mus musculus