Title : GalNAc-alpha-O-benzyl inhibits NeuAcalpha2-3 glycosylation and blocks the intracellular transport of apical glycoproteins and mucus in differentiated HT-29 cells.

Pub. Date : 1998 Jun 15

PMID : 9628888






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Exposure for 24 h of mucus-secreting HT-29 cells to the sugar analogue GalNAc-alpha-O-benzyl results in inhibition of Galbeta1-3GalNAc:alpha2,3-sialyltransferase, reduced mucin sialylation, and inhibition of their secretion (Huet, G., I. Kim, C. de Bolos, J.M. N-acetylgalactosaminuronic acid ST3 beta-galactoside alpha-2,3-sialyltransferase 1 Homo sapiens