Protein Name ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Organism Homo sapiens
Gene ID 6482
Gene Symbol

ST3GAL1

UniProt Q11201 (SIA4A_HUMAN), A0A024R9L6 (A0A024R9L6_HUMAN)
Relationships Total Number of functionally related compound(s) : 54
Total Number of Articles : 46
Description

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

Gene Summary

The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]

synonyms
  • CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
  • Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase
  • SIAT4-A
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Properties