Pub. Date : 1998 Feb
PMID : 9621392
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine has been shown to be a potent stimulus for the secretion of the stress-responsive hormones, adrenocorticotropin (ACTH) and prolactin. | Nicotine | proopiomelanocortin | Homo sapiens |
| 2 | Data are presented demonstrating that nicotine acts via a central mechanism to stimulate indirectly the release of ACTH from the anterior pituitary corticotropes. | Nicotine | proopiomelanocortin | Homo sapiens |
| 3 | A reduction in the modulatory effect of these catecholamines (by neurotoxic lesion, synthetic enzyme inhibitors or adrenergic receptor antagonists) resulted in an inhibition of nicotine-stimulated ACTH secretion. | Nicotine | proopiomelanocortin | Homo sapiens |