PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9621392-1 1998 Nicotine has been shown to be a potent stimulus for the secretion of the stress-responsive hormones, adrenocorticotropin (ACTH) and prolactin. Nicotine 0-8 proopiomelanocortin Homo sapiens 122-126 9621392-4 1998 Data are presented demonstrating that nicotine acts via a central mechanism to stimulate indirectly the release of ACTH from the anterior pituitary corticotropes. Nicotine 38-46 proopiomelanocortin Homo sapiens 115-119 9621392-7 1998 A reduction in the modulatory effect of these catecholamines (by neurotoxic lesion, synthetic enzyme inhibitors or adrenergic receptor antagonists) resulted in an inhibition of nicotine-stimulated ACTH secretion. Nicotine 177-185 proopiomelanocortin Homo sapiens 197-201