Pub. Date : 1998 Jun 9
PMID : 9618521
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We show that IL-2 induces tyrosine phosphorylation of a 125-kDa protein and homotypic adhesion in beta2 integrin (CD18)-positive but not in beta2-integrin-negative T cells. | Tyrosine | interleukin 2 | Homo sapiens |
2 | EDTA, an inhibitor of integrin adhesion, blocks IL-2-induced tyrosine phosphorylation of the 125-kDa protein but not other proteins in beta2-integrin-positive T cells. | Tyrosine | interleukin 2 | Homo sapiens |
3 | Thus, IL-2 induces strong tyrosine phosphorylation of fakB in beta2-integrin-positive but not in beta2-integrin-negative T cells, and CD18 mAb selectively blocks IL-2-induced fakB-tyrosine phosphorylation in beta2-integrin-positive T cells. | Tyrosine | interleukin 2 | Homo sapiens |
4 | Thus, IL-2 induces strong tyrosine phosphorylation of fakB in beta2-integrin-positive but not in beta2-integrin-negative T cells, and CD18 mAb selectively blocks IL-2-induced fakB-tyrosine phosphorylation in beta2-integrin-positive T cells. | Tyrosine | interleukin 2 | Homo sapiens |
5 | Thus, IL-2 induces strong tyrosine phosphorylation of fakB in beta2-integrin-positive but not in beta2-integrin-negative T cells, and CD18 mAb selectively blocks IL-2-induced fakB-tyrosine phosphorylation in beta2-integrin-positive T cells. | Tyrosine | interleukin 2 | Homo sapiens |