Pub. Date : 1998 Jun
PMID : 9603221
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we show that both the tricyclic antidepressant imipramine and the nontricyclic antidepressant citalopram competitively inhibit 5-HT transport mediated by the recombinant rat 5-HT transporter SERT1. | Imipramine | solute carrier family 6 member 4 | Rattus norvegicus |
| 2 | Thus, depending on which of its binding sites on SERT1 is occupied, imipramine may exert distinct effects on 5-HT uptake mediated by the recombinant rat 5-HT transporter. | Imipramine | solute carrier family 6 member 4 | Rattus norvegicus |