Title : A237T as a modulating mutation in naturally occurring extended-spectrum TEM-type beta-lactamases.

Pub. Date : 1998 May

PMID : 9593123






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A TEM-1 beta-lactamase derivative containing the single amino acid substitution A237T slightly increased (from 24 to 32 microg/ml) the cephalothin MIC for Escherichia coli RYC1000 but did not influence the activities of cefotaxime, ceftazidime, and aztreonam (MICs of 0.03, 0.12, and 0.06 microg/ml, respectively). Aztreonam TEM-1 beta-lactamase Escherichia coli