Title : Syk activation is required for spreading and H2O2 release in adherent human neutrophils.

Pub. Date : 1998 May 15

PMID : 9590268






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Pretreatment of PMNs with piceatannol, a Syk-selective inhibitor, blocked Syk activity, cell spreading, and H2O2 release, indicating that Syk activity was required for the activation of adherent PMNs. 3,3',4,5'-tetrahydroxystilbene spleen associated tyrosine kinase Homo sapiens
2 Pretreatment of PMNs with piceatannol, a Syk-selective inhibitor, blocked Syk activity, cell spreading, and H2O2 release, indicating that Syk activity was required for the activation of adherent PMNs. 3,3',4,5'-tetrahydroxystilbene spleen associated tyrosine kinase Homo sapiens
3 Pretreatment of PMNs with piceatannol, a Syk-selective inhibitor, blocked Syk activity, cell spreading, and H2O2 release, indicating that Syk activity was required for the activation of adherent PMNs. 3,3',4,5'-tetrahydroxystilbene spleen associated tyrosine kinase Homo sapiens
4 Paxillin phosphorylation is kinetically slower than Syk phosphorylation and is inhibited with piceatannol, suggesting that paxillin is a substrate for Syk. 3,3',4,5'-tetrahydroxystilbene spleen associated tyrosine kinase Homo sapiens