Title : Histamine-stimulated cytokine secretion from human conjunctival epithelial cells: inhibition by the histamine H1 antagonist emedastine.

Pub. Date : 1998 Apr

PMID : 9566351






2 Functional Relationships(s)
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1 The present studies demonstrate that histamine induces the secretion of IL-6, IL-8 and GM-CSF from human conjunctival epithelial cells in a dose- and time-dependent manner. Histamine colony stimulating factor 2 Homo sapiens
2 Emedastine potently inhibited histamine-induced IL-6, IL-8 and GM-CSF secretion with mean IC50 values of 2.23, 3.42 and 1.50 nM, respectively. Histamine colony stimulating factor 2 Homo sapiens