Title : Necessity of interleukin-1beta converting enzyme cascade in taxotere-initiated death signaling.

Pub. Date : 1998 Feb 5

PMID : 9551718






1 Functional Relationships(s)
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1 When cells were pretreated with the synthesized tetrapeptide inhibitor of caspase, YVAD-CHO (Ac-Tyr-Val-Ala-Asp-aldehyde: inhibitor of interleukin-1beta converting enzyme (ICE) subfamily) or DEVD-CHO (Ac-Asp-Glu-Val-Asp-aldehyde: inhibitor of CPP32 subfamily), taxotere-induced cell death was prevented. tyrosyl-valyl-alanyl-aspartal caspase 3 Mus musculus