Pub. Date : 1998 Mar
PMID : 9548588
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interaction of pulmonary surfactant protein A with dipalmitoylphosphatidylcholine and cholesterol at the air/water interface. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |
| 2 | Interaction of pulmonary surfactant protein A (SP-A) with pure and binary mixed dipalmitoylphosphatidylcholine (DPPC) and cholesterol (3.5 wt%) at the air/saline, 1.5 mM CaCl2 interface was investigated using a rhomboid surface balance at 37 degrees C. Surface tension-area isotherms were measured to access the surface active properties of the monolayers. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |
| 3 | Interaction of pulmonary surfactant protein A (SP-A) with pure and binary mixed dipalmitoylphosphatidylcholine (DPPC) and cholesterol (3.5 wt%) at the air/saline, 1.5 mM CaCl2 interface was investigated using a rhomboid surface balance at 37 degrees C. Surface tension-area isotherms were measured to access the surface active properties of the monolayers. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |
| 4 | The results showed that SP-A can interact with the polar head groups of DPPC monolayers and aggregate DPPC molecules. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |
| 5 | The results showed that SP-A can interact with the polar head groups of DPPC monolayers and aggregate DPPC molecules. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |
| 6 | SP-A decreased the surface area reduction required for DPPC monolayers to achieve near zero surface tension from 30 to 25% of the area at equilibrium. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |
| 7 | Although SP-A could not promote the squeeze-out of cholesterol from homogeneous mixed monolayers, it facilitated that of cholesterol domains especially when SP-A had first interacted with DPPC. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |
| 8 | These results indicate that pulmonary surfactant protein A facilitates the squeeze-out of cholesterol domains from mixed monolayers by condensing DPPC and limiting lateral interactions of DPPC with cholesterol domains. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |
| 9 | These results indicate that pulmonary surfactant protein A facilitates the squeeze-out of cholesterol domains from mixed monolayers by condensing DPPC and limiting lateral interactions of DPPC with cholesterol domains. | 1,2-Dipalmitoylphosphatidylcholine | surfactant protein A1 | Homo sapiens |