Pub. Date : 1998 Apr
PMID : 9545996
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Binding of antipsychotic drugs to cortical 5-HT2A receptors: a PET study of chlorpromazine, clozapine, and amisulpride in schizophrenic patients. | Chlorpromazine | 5-hydroxytryptamine receptor 2A | Homo sapiens |
| 2 | OBJECTIVE: This study examined the binding to cortical serotonin 5-HT2A receptors of conventional doses of the typical neuroleptic chlorpromazine in comparison with clozapine, the prototype atypical antipsychotic, and amisulpride, a specific dopamine D2-D3 blocker. | Chlorpromazine | 5-hydroxytryptamine receptor 2A | Homo sapiens |
| 3 | This suggests a high level of 5-HT2A blockade with both clozapine and high doses of chlorpromazine. | Chlorpromazine | 5-hydroxytryptamine receptor 2A | Homo sapiens |