Title : Aliphatic and alicyclic diols induce melanogenesis in cultured cells and guinea pig skin.

Pub. Date : 1998 Apr

PMID : 9540987






2 Functional Relationships(s)
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1 Following treatment with these diols or 3-isobutyl-1-methylxanthine, melanin and tyrosinase activity are increased within S91 cells and NHEM; however, for cultured NHEM, the largest increases of melanin and tyrosinase occur in an extracellular particulate fraction, shown by electron microscopy to consist almost entirely of stage III and IV melanosomes. 1-Methyl-3-isobutylxanthine tyrosinase Mus musculus
2 Following treatment with these diols or 3-isobutyl-1-methylxanthine, melanin and tyrosinase activity are increased within S91 cells and NHEM; however, for cultured NHEM, the largest increases of melanin and tyrosinase occur in an extracellular particulate fraction, shown by electron microscopy to consist almost entirely of stage III and IV melanosomes. 1-Methyl-3-isobutylxanthine tyrosinase Mus musculus