Pub. Date : 1998 Apr 14
PMID : 9539776
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | However, in the transgenic hearts with overexpression of SOD1 the burst of superoxide generation was almost totally quenched, and this was accompanied by a 2-fold increase in the recovery of contractile function, a 2.2-fold decrease in infarct size, and a greatly improved recovery of high energy phosphates compared with that in nontransgenic controls. | Superoxides | superoxide dismutase 1, soluble | Mus musculus |
2 | These results demonstrate that superoxide is an important mediator of postischemic injury and that increasing intracellular SOD1 dramatically protects the heart from this injury. | Superoxides | superoxide dismutase 1, soluble | Mus musculus |