Title : Functional expression of P-glycoprotein in the hepatic canalicular membrane of developing rats.

Pub. Date : 1998 Mar

PMID : 9523982






3 Functional Relationships(s)
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1 The transport of daunomycin (DNM), a P-gp substrate, was used to study age-related functional differences in P-gp. Daunorubicin ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus
2 The transport of daunomycin (DNM), a P-gp substrate, was used to study age-related functional differences in P-gp. Daunorubicin ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus
3 DNM uptake in the presence of ATP was greater than uptake in the absence of ATP in both young and adult cLPM vesicles, showing that P-gp is functional in both groups. Daunorubicin ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus