Protein Name ATP-binding cassette, sub-family B member 1B
Organism Rattus norvegicus
Gene ID 24646
Gene Symbol


UniProt Q8R427 (Q8R427_RAT)
Relationships Total Number of functionally related compound(s) : 765
Total Number of Articles : 1099

ATP-binding cassette, sub-family B member 1B

Gene Summary

Predicted to enable ATPase-coupled intramembrane lipid transporter activity; ATPase-coupled transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in several processes, including Sertoli cell barrier remodeling; animal organ development; and cellular response to external biotic stimulus. Located in Golgi membrane and external side of apical plasma membrane. Used to study brain disease (multiple); colorectal adenocarcinoma; end stage renal disease; and human immunodeficiency virus infectious disease. Biomarker of brain disease (multiple); cholestasis; human immunodeficiency virus infectious disease; non-alcoholic fatty liver disease; and obstructive sleep apnea. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); human immunodeficiency virus infectious disease (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Orthologous to human ABCB1 (ATP binding cassette subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]

  • ATP-dependent translocase ABCB1
  • ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1)
  • ATP-binding cassette sub-family B member 1
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