Pub. Date : 1998 Mar
PMID : 9506439
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Transfection of the CAT-involucrin promoter expression vector with PKC-alpha or PKC-eta expression vectors resulted in a significant increase in the TPA-dependent involucrin promoter activity. | Tetradecanoylphorbol Acetate | endothelin receptor type A | Homo sapiens |
| 2 | Gel retardation analyses disclosed that TPA stimulated the specific DNA binding of the nuclear protein(s) of control, PKC-alpha, or PKC-eta-transfected SVHK cells, but not of PKC-gamma-transfected cells. | Tetradecanoylphorbol Acetate | endothelin receptor type A | Homo sapiens |
| 3 | These results indicate that PKC, specifically PKC-alpha and PKC-eta, mediates the TPA-dependent activation of involucrin gene expression of SVHK cells. | Tetradecanoylphorbol Acetate | endothelin receptor type A | Homo sapiens |