Title : Discovery of a structurally novel opioid kappa-agonist derived from 4,5-epoxymorphinan.

Pub. Date : 1998 Feb

PMID : 9501472






1 Functional Relationships(s)
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1 A unique structural feature of TRK-820, which is different from other prototypical kappa-opioid receptor agonists, is the existence of the 4,5-epoxymorphinan structure with a tyrosine-glysine moiety for endogenous opioid peptides such as dynorphins. Tyrosine neurotrophic tyrosine kinase, receptor, type 1 Mus musculus