| Protein Name | neurotrophic tyrosine kinase, receptor, type 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18211 |
| Gene Symbol | Ntrk1 |
| UniProt | Q3UFB7 (NTRK1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
164
Total Number of Articles : 166 |
Description |
neurotrophic tyrosine kinase, receptor, type 1 |
| Gene Summary |
Predicted to enable several functions, including GPI-linked ephrin receptor activity; nerve growth factor binding activity; and nerve growth factor receptor activity. Involved in axonogenesis involved in innervation; negative regulation of neuron apoptotic process; and sympathetic nervous system development. Acts upstream of or within several processes, including behavioral response to formalin induced pain; nerve growth factor signaling pathway; and nervous system development. Located in axon; cell surface; and endosome. Is expressed in several structures, including branchial arch; gonad; nervous system; sensory organ; and urogenital ridge. Used to study hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in Alzheimer's disease; hereditary sensory neuropathy; hereditary sensory neuropathy type 4; and schizophrenia. Orthologous to human NTRK1 (neurotrophic receptor tyrosine kinase 1). [provided by Alliance of Genome Resources, Apr 2022] |
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