Pub. Date : 1998 Feb 27
PMID : 9478967
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | These results show that triggering the ceramide signaling pathway activates MMP-1 gene expression via three distinct MAPK pathways, i.e. ERK1/2, SAPK/JNK, and p38, and suggest that targeted modulation of the ceramide signaling pathway may offer a novel therapeutic approach for inhibiting collagenolytic activity, e.g. in inflammatory disorders. | Ceramides | mitogen-activated protein kinase 8 | Homo sapiens |