Pub. Date : 1997 Dec
PMID : 9447833
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UCB progenitor cells showed a higher resistance to mafosfamide treatment, in comparison to BM; the addition of SCF to the culture medium resulted in a statistically significant increase in mafosfamide concentration required to inhibit 95% of colony growth (P < or = 0.05). | mafosfamide | KIT ligand | Homo sapiens |
| 2 | UCB progenitor cells showed a higher resistance to mafosfamide treatment, in comparison to BM; the addition of SCF to the culture medium resulted in a statistically significant increase in mafosfamide concentration required to inhibit 95% of colony growth (P < or = 0.05). | mafosfamide | KIT ligand | Homo sapiens |
| 3 | Moreover, as shown by single colony transfer assays, the presence of SCF in primary cultures promoted a significantly higher replating potential for both untreated (42 +/- 3.3% vs 21 +/- 4.6%, P < or = 0.018) and mafosfamide-treated samples (62 +/- 5.6% vs 44 +/- 6.1%, P < or = 0.018). | mafosfamide | KIT ligand | Homo sapiens |