Title : Thrombin-induced thromboxane synthesis by human platelets. Properties of anion binding exosite I-independent receptor.

Pub. Date : 1997 Dec

PMID : 9437201






2 Functional Relationships(s)
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1 Stimulation through the second receptor/substrate depends on a genistein-sensitive step, is independent of an intracellular Ca2+ flux, and is initiated by a thrombin-activated receptor that does not depend on interaction with anion-binding exosite I, as previously indicated by the relative activity of Thrombin Quick I in stimulating platelet aggregation and thromboxane production. Genistein coagulation factor II, thrombin Homo sapiens
2 Stimulation through the second receptor/substrate depends on a genistein-sensitive step, is independent of an intracellular Ca2+ flux, and is initiated by a thrombin-activated receptor that does not depend on interaction with anion-binding exosite I, as previously indicated by the relative activity of Thrombin Quick I in stimulating platelet aggregation and thromboxane production. Genistein coagulation factor II, thrombin Homo sapiens