Title : Developmental expression of CYP2C and CYP2C-dependent activities in the human liver: in-vivo/in-vitro correlation and inducibility.

Pub. Date : 1997 Dec

PMID : 9429229






1 Functional Relationships(s)
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1 In adult liver preparations, the hydroxylation of diazepam correlated well with the CYP3 A content of microsomes (r = 0.858, p < 0.01) and with the 6 beta hydroxylation of testosterone (r = 0.830, p < 0.005), whereas demethylation was related to the bulk of CYP2C proteins (r = 0.865, p < 0.005). Diazepam cytochrome P450 family 3 subfamily A member 4 Homo sapiens