Title : Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency.

Pub. Date : 1998 Jan 1

PMID : 9412501






1 Functional Relationships(s)
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1 Sod2 -/+ mice demonstrated a prominent increase in O2- production under normal physiological conditions and in ischemia, as evidenced by specific oxidation of a fluorescent probe, hydroethidine, reflecting decreased activity of Mn-SOD. Superoxides superoxide dismutase 2, mitochondrial Mus musculus