Title : Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation.

Pub. Date : 1997 Dec 26

PMID : 9407097






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, we have used the above parameters to study the interactions between tau protein and a number of naturally occurring and synthetic glycosaminoglycans. Glycosaminoglycans microtubule associated protein tau Homo sapiens
2 These in vitro interactions between tau protein and sulfated glycosaminoglycans reproduced the known characteristics of paired helical filament-tau from Alzheimer"s disease brain. Glycosaminoglycans microtubule associated protein tau Homo sapiens
3 These in vitro interactions between tau protein and sulfated glycosaminoglycans reproduced the known characteristics of paired helical filament-tau from Alzheimer"s disease brain. Glycosaminoglycans microtubule associated protein tau Homo sapiens